Author

Jing-Xian Li

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Open access Aug 2026

NEK2-AURKA axis drives ubiquitin-dependent IFT88 degradation to suppress ciliogenesis and promote basal-type bladder cancer

A NEK2-AURKA-IFT88 pathway that promotes ubiquitin-dependent IFT88 degradation and cilia loss in basal MIBC models is identified, providing a preclinical basis for further testing of NEK2 targeting in cilia-deficient basal MIBC.

E. Du, Wei Wang, Qiang Su et al. · Cell Death & Disease · 0 citations

Open access Aug 2026

Integrative bulk and single-cell transcriptomics identify a recurrence-prognostic risk model with exploratory associations with treatment-response phenotypes in colorectal cancer

A READ-derived response-associated gene signature for recurrence stratification and exploratory cross-cohort evaluation in additional colorectal cancer cohorts, while further exploring its association with treatment-response phenotypes.

Shuai Li, Jing-Xian Li, Xianyue Bu et al. · Human Cell · 0 citations