Jing-Xiong Xu

Abstract B036: Systematic Germline and Tumor Genomic Analysis for Gene Discovery in Familial Pancreatic Cancer

Despite the identification of several pancreatic ductal adenocarcinoma (PDAC) predisposition genes, more than 75% of familial pancreatic cancer (FPC) families remain genetically unexplained. To address this, we developed a systematic discovery pipeline focused on families with multiple affected individuals, leveragin...