Serum Pharmacochemistry and Metabolomics Reveal the Mechanism of Hedan Tablets Combined With Simvastatin in Hyperlipidemia Treatment.
Simvastatin (ST) is commonly used to treat hyperlipidemia (HLP), but it has serious side effects, such as myopathy and hepatotoxicity. Clinically, statins are often combined with Hedan tablets (HDT) to treat HLP, but the composition and mechanism of their pharmacological effects are still unclear. Therefore, the purpos...