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Open access Aug 2026

Hairpin-Structured DNAzyme-Initiated Spherical Hybridization Chain Reaction Cascade Enables Highly Sensitive Electrochemical Detection of MicroRNA

Sensitive and accurate detection of low-abundance microRNAs (miRNAs) in complex biological matrices is critical for early disease diagnosis. Herein, we report a homogeneous cascade amplification-based electrochemical biosensing platform that integrates hairpin-structured DNAzyme-assisted target recycling amplification...

Yue-Lin Zhou, Jing Yang, Jing-Ran Weng et al. · 0 citations

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