Neutrophil Senescence Induced by Tumor-Derived HMGB1 Promotes Hepatocellular Carcinoma Progression through Neutrophil Extracellular Trap-Mediated Suppression of CD8+ T Cell Immunity
Background: Immune cells are essential components of the tumor microenvironment. Among them, neutrophils have gained increasing interest due to their marked heterogeneity. This study focused on aged neutrophils, aiming to uncover their mechanistic contribution to hepatocellular carcinoma (HCC) progression and evaluate...