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Open access Jan 2026

Revealing the Diagnostic Potential of Three RHO GTPase‐Related Genes in Osteoarthritis Based on Single‐Cell RNA Sequencing and GEO Dataset Analysis

Background Osteoarthritis (OA) is becoming increasingly common, and RHO GTPase family members have been implicated in inflammatory processes associated with OA. We therefore examined the diagnostic utility of RHO GTPase‐related genes (RGPRGs) in OA. Methods The OA expression datasets were collected from public reposito...

Guo-Qiang Zou, Xu-Feng Wang, Jing Yu · 0 citations
Clinical trial Open access Sep 2026

Pharmacokinetic and Bioequivalence Evaluation of Febuxostat 40 mg Tablets in Healthy Chinese Subjects Under Fasting and Fed Conditions.

The objective of the current study was to evaluate the rate and extent of absorption, and confirm the bioequivalence of a test formulation and a reference formulation of febuxostat 40 mg tablets in healthy Chinese subjects under both fasting and fed conditions. An open-label, randomized, single-dose, single-center, two...

Ying Cao, Wen-Ping Wang, Xiao-Bin Li et al. · 0 citations

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