Receptor-interacting Protein Kinase 1 Regulates Microglial Polarization via the Csf3-JAK2/STAT3 Axis in Lipopolysaccharide-Induced inflammation and Lysolecithin-Induced Demyelination.
In numerous demyelinating diseases, brain tissue exhibits excessive inflammatory responses that promote the activation of immune cells, thereby exacerbating cellular damage and amplifying inflammatory cascades. Emerging evidence highlights receptor-interacting protein kinase 1 (RIPK1) is a pivotal regulator of neuroinf...