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Author

Jing Zhang

2 papers indexed here

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Aug 2026

The mechanism of SOX4/IGF2BP3/TRIB3 axis inhibiting autophagy and aggravating liver injury in sepsis.

Sepsis-associated liver injury (SALI) is a serious complication with limited treatment options. While protective autophagy is often suppressed in sepsis, the underlying mechanisms remain unclear. This study investigated whether the SOX4/IGF2BP3/TRIB3 pathway contributes to liver dysfunction by suppressing cytoprotectiv...

Wen-Jun Zhao, Jing Zhang, Liang Zhang et al. · 0 citations
Open access Aug 2026

IGF2BP3-mediated regulation of the RNA isoform and modification landscape in pancreatic cancer.

The incidence of pancreatic ductal adenocarcinoma (PDAC) is increasing but clinical outcomes remain poor and new treatments are required. IGF2BP3 is an oncofetal m6A-reading RNA regulatory protein whose expression is commonly observed in PDAC and which may represent an important therapeutic target. IGF2BP3 protein is e...

Sandra Margielewska-Davies, W. Croft, Hayden Pearce et al. · 0 citations

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