This review integrates current evidence within an NVU-centered systems biology framework and aligns therapeutic strategies with the disease hierarchy, distinguishing established clinical treatments from preclinical and emerging interventions.
Chun-Ning Zhao, Lei-Lei Qin, Jing Zhang et al.· Stem Cell Reviews and Report...· 1 citation
Liddle syndrome (LS) is a rare autosomal dominant condition classically defined by early-onset hypertension, hypokalemia, metabolic alkalosis, and a suppressed renin-aldosterone profile, primarily driven by gain-of-function mutations in the
SCNN1A
,
SCNN1B
, or
SCNN1G
genes encoding the epithelial sodium...
Yun-Long Liang, Ya Zheng, Hua Yuan et al.· Journal of Medical Case Repo...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.