Jingchun Li

Integrative multi-omics and machine learning analysis identifies candidate biomarkers associated with mitochondrial quality control in major depressive disorder

Background Major depressive disorder (MDD) possesses a complex pathogenesis, with abnormal mitochondrial quality control (MQC) proposed as a potential mechanism involved in the pathological process. Methods This study integrated two microarray expression profiling datasets with a single-nucleus RNA sequencing (snRNA-se...