Jingru Wang

Pharmacological Targeting of Kidney Fibrosis: Druggable Mechanisms, Translational Models, and Emerging Antifibrotic Therapies

This review examines emerging mechanisms that govern kidney fibrogenesis, with emphasis on therapeutic tractability, and considers how experimental models can improve target prioritization and drug development, and summarizes repurposed drugs, pathway-targeted agents, receptor-directed strategies and cell-based approaches under preclinical or clinical evaluation.