Electroporation-primed cascade nanocatalysis boosts STING-driven chemoimmunotherapy in hepatocellular carcinoma
Nanosecond pulsed electric field (nsPEF) ablation enables non-thermal tumor destruction with favorable tissue selectivity, but its long-term efficacy is often limited by postoperative recurrence. Here, we developed an electroporation-primed, tumor microenvironment-responsive core-shell cascade nanoparticle, ZnO2-NiFc@M...