Caenorhabditis elegans: A Versatile In vivo Model for Decoding Conserved Oncogenic Signaling Pathways.
Caenorhabditis elegans (C. elegans) is a genetically tractable, transparent, and cost-effective metazoan model that bridges conventional cell-culture assays and mammalian systems for mechanistic cancer research. This pathway-focused review covers representative studies of conserved RAS/MAPK, Notch, and Wnt signaling an...