Aug 2026
CNOT1 is a potential YTHDF2 target that orchestrates maternal mRNA decay and zygotic genome activation during goat embryogenesis.
It is found that CNOT1 was upregulated during mammalian ZGA, and that its knockdown led to developmental arrest and a marked reduction in blastocyst formation, which indicates that CNOT1 is a potential YTHDF2 target that orchestrates maternal mRNA decay and ZGA during goat embryogenesis.
Xiaowei Chen, Yingnan Yang, Jinhao Zhang et al.
· Animal Reproduction Science · 0 citations