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Jinmiao Li

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Open access Aug 2026

Targeting MYCN Degradation by HLB-0532259 Induces Senescence in Retinoblastoma

Targeted MYCN degradation by HLB-0532259 effectively inhibits RB growth and induces a DNA damage–associated senescence program, highlighting targeted MYCN degradation as a promising therapeutic strategy for MYCN-driven RB.

Junjie Tang, Zhihui Zhang, Jianjie Lv et al. · 0 citations

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