Ginsenoside Rg3 attenuates osteoarthritis progression by modulating the Nrf2-mediated autophagy pathway.
PURPOSE Osteoarthritis (OA) is a chronic and progressive joint disorder characterized by persistent inflammation, extracellular matrix (ECM) disruption, and chondrocyte apoptosis. This study aimed to investigate the protective effects of ginsenoside Rg3 (Rg3), a natural steroidal saponin from Panax ginseng, on OA and t...