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Author

Jit Chatterjee

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Review Open access Oct 2026

Poly(I:C) suppresses NF1-associated optic pathway glioma growth through TLR3-dependent and TLR3-independent modulation of microglial ERK signaling

Immunomodulatory therapies have emerged as promising treatments for cancer, where poly(I:C), a synthetic double-stranded RNA, is currently under clinical investigation for its ability to control myeloid cell function and T cell infiltration. While poly(I:C) mimics viral infection and activates Toll-like receptor 3...

Jit Chatterjee, Elvedina Subasic, Megan Ouyang et al. · 0 citations

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