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Jiu-Fan He

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Open access Sep 2026

Genetically Predicted Intervertebral Disc Degeneration and Risk of Osteoarthritis: A Two-Sample Mendelian Randomization Study with Mediation Analysis of Obesity and Sarcopenia

Background Chronic pain related to spinal degeneration and osteoarthritis (OA) represents a major cause of disability worldwide. However, whether intervertebral disc degeneration (IVDD) contributes to OA and related pain burden remains unclear. Objective To investigate the potential causal relationship between genetica...

Jun-Yu Zhu, Zun-Yu Li, Shi-Jie Zhou et al. · 0 citations

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