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Jiu-Xing Li

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Open access Sep 2026

Competitive SELEX Strategy for High-Affinity Aptamer Isolation and Enhanced Biosensing.

Aptamers, with their high specificity and affinity, are invaluable for diagnostics and therapeutics. However, conventional SELEX (Systematic Evolution of Ligands by Exponential Enrichment) often favors abundant low-affinity sequences, limiting the isolation of rare, high-affinity candidates. To overcome this challenge,...

Jiu-Xing Li, Jia-Xuan Xiao, Jimmy Gu et al. · 0 citations
Open access Sep 2026

Multi-affinity electrochemical perfluorooctanoic acid sensing enabled by a microenvironment-engineered MOF synergy

The accumulation of perfluorooctanoic acid (PFOA) in environmental waters poses substantial environmental and health risks, even at trace levels, owing to its environmental persistence. Here we developed an electrochemical sensor integrating molecularly imprinted polymers with functionalized metal–organic frameworks (M...

Kai Niu, Jiu-Xing Li, Rui Zhang et al. · 0 citations

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