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Jiu-Yao Wang

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Open access Oct 2026

Divergent Roles of PIK3C3 in KRAS‐Wild‐Type and KRAS‐Mutant Advanced Colorectal Cancer: Implications for 5‐Fluorouracil Sensitivity and Prognosis

ABSTRACT Introduction Phosphatidylinositol 3‐kinase catalytic subunit type 3 (PIK3C3) is central to autophagy, which supports cancer adaptation to environmental stresses and may contribute to drug resistance. KRAS‐mutant cancers have been reported to require autophagy for survival. We investigated the influence of KRAS...

Chien-An Chu, Nan-Haw Chow, Jiu-Yao Wang et al. · 0 citations
Review Open access Sep 2026

Gram-Positive and Gram-Negative Probiotic Extracellular Vesicles: Mechanisms of Immune Modulation and Therapeutic Opportunities in Atopic Dermatitis

Atopic dermatitis (AD) is a prevalent chronic inflammatory skin disease characterized by epidermal barrier dysfunction, type 2 immune skewing, and microbiome dysbiosis. Although live probiotics can modulate the gut-skin axis, their clinical use is limited by variable efficacy and safety concerns. Probiotic extracellula...

V. Wayal, Mey-Fann Lee, Jiu-Yao Wang et al. · 1 citation

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