Author

Joanna Wa̧tły

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Open access Sep 2026

Coordination chemistry and antimicrobial activity of LL-37, its C-terminal fragment, and a peptidomimetic analogue.

Human cathelicidin LL-37 is an antimicrobial peptide naturally present in saliva that plays an important role in host defence against bacterial and fungal pathogens. Although LL-37 is known to bind Cu(II) and Zn(II) ions, the corresponding coordination modes have remained unresolved. Here, the metal-binding properties,...

Klaudia Szarszoń, Marta Luszawska, Michał Jewgiński et al. · Dalton Transactions · 0 citations

Open access Jul 2026

Beyond proteolysis: rational modification of mucin-derived peptidomimetics with enhanced metal-mediated antimicrobial activity

It is demonstrated that d-amino-acid incorporation combined with metal coordination significantly improves both enzymatic stability and antimicrobial performance of mucin-derived peptides.

A. Ślusarczyk, D. Bellotti, Silvia Leveraro et al. · RSC Advances · 0 citations