Open access
Aug 2026
Performance of PREMM5, clinical criteria, and immunohistochemistry for MMR proteins in genetic risk assessment of Mexican patients with colorectal cancer
Background All individuals with colorectal cancer (CRC) should undergo genetic cancer risk assessment given its implications for personalized treatment, surveillance, risk-reduction strategies, and cascade testing. Universal screening using immunohistochemistry (IHC) for mismatch repair (MMR) proteins in tumor tissue,...
J. L. Rodríguez-Olivares, D. Aguilar-y-Mendez, Tamara N. Kimball et al.
· PLoS ONE · 0 citations