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Joaquín Cantón-Sandoval

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Open access Jul 2026

Embryonic TGF-β signaling imposes persistent changes to HSPC clonality and inflammatory landscape

Transient developmental signaling perturbations reshape hematopoietic trajectories produce sustained effects on hematopoietic and immune function into adulthood, including diminished inflammatory gene expression, reduced clonal complexity, and impaired regenerative capacity.

Marta Mastrogiovanni, Anastasia Nizhnik, Joaquín Cantón-Sandoval et al. · 0 citations

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