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Author

Joaquín Cantón-Sandoval

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Open access Oct 2026

Activation of Innate and Adaptive Immunity in the Central Nervous System Following Xenogeneic Mesenchymal Stromal Cell Transplantation

Stem cell-based therapies have emerged as promising strategies for neurodegenerative disorders, partly supported by the concept of central nervous system immune privilege, which has encouraged xenogeneic transplantation approaches under the assumption of limited host immune responses. However, the immunological consequ...

María Norte-Muñoz, Joaquín Cantón-Sandoval, Fernando Lucas-Ruiz et al. · 0 citations
Open access Jul 2026

Embryonic TGF-β signaling imposes persistent changes to HSPC clonality and inflammatory landscape

Transient developmental signaling perturbations reshape hematopoietic trajectories produce sustained effects on hematopoietic and immune function into adulthood, including diminished inflammatory gene expression, reduced clonal complexity, and impaired regenerative capacity.

Marta Mastrogiovanni, Anastasia Nizhnik, Joaquín Cantón-Sandoval et al. · 0 citations

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