Open access
Sep 2026
Dengue virus 2 lacking N153 glycosylation displayed enhanced recognition by neutralizing antibodies
Deglycosylated (N153Q) dengue virus (DENV) mutant shows attenuated infection in a mouse model, mainly due to its increased antibody susceptibility. This is consistent with the neutralization assay showing human monoclonal antibodies 2D22 and C10 are more potent towards the mutant than the wild-type (WT) virus. Here,...
G. Fibriansah, T. Ng, X. Lim et al.
· npj Viruses · 0 citations