Johanna H. Meijer

Identification of small-molecule enhancers of circadian rhythm amplitude in central and peripheral clocks

The circadian clock regulates daily rhythms in metabolism, behavior, and physiological homeostasis. Damped or disrupted circadian rhythms are linked to physiological malfunctions, including neurodegeneration, metabolic syndrome, and cancers. Enhancing circadian rhythm amplitude can strengthen the processes regulated th...