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Author

Johannes Breithofer

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Open access Sep 2026

Batten disease protein CLN8 enables a non-canonical phospholipid synthesis pathway

According to text book knowledge, de novo glycerophospholipid (GPL) synthesis begins with the acylation of glycerol-3-phosphate to form phosphatidic acid, the precursor of all other GPLs. Here we describe an alternative GPL synthesis pathway that starts with the acyl-CoA-dependent acylation of glycerophosphoglycerol, r...

Johannes Breithofer, Nermeen Fawzy, C. Zitta et al. · 3 citations

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