Open access
Sep 2026
AP-1 specifies developmental versus fibrotic extracellular matrix transcriptional programs in the lung
Lung function requires an elastic extracellular matrix (ECM). However, the adult lung does not regenerate the elastic architecture established during development, and deposition of fibrous ECM characterizes many lung diseases. We generated a multimodal, single-nuclei atlas across development, homeostasis, aging, and fi...
A. Kaiser, Angela Luo, Kathyayini Sivasubramanian et al.
· bioRxiv · 0 citations