Author

Johannes Zuegg

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Open access Aug 2026

Mapping the resistance landscape: A large-scale study of polymyxin-resistant pathogens circulating in low-and middle-income countries

The increasing prevalence of antimicrobial resistance is a major public health challenge, particularly in low- and middle-income countries (LMICs). Polymyxins are last-resort antibiotics used for treating highly drug-resistant infections, however, the rise of polymyxin-resistant bacterial strains is further reducing tr...

T. Duarte, Holly Floyd, V. Thamlikitkul et al. · Research Square · 0 citations

#explainable ai Open access Sep 2026

Fragment-Based Explainable AI for Pathogen-Selective Antimicrobial Drug Design

The rise and extent of antimicrobial resistance demand computational tools that go beyond simple predictions of antimicrobial activity to deliver applicable medicinal chemistry insights for an accelerated and more efficient development of novel antimicrobials. Here, we present a fragment-based explainable artificial...

Abdulmujeeb T. Onawole, M. Blaskovich, Johannes Zuegg · ACS Infectious Diseases · 0 citations