Mycobacterium Tuberculosis Drug Resistance Prediction from Whole Genome Sequences Using Hierarchical CNN-Transformer Mutation Pattern Encoding
A Hierarchical CNN-Transformer Mutation Pattern Encoding (HCT-MPE) framework that hierarchically encodes nucleotide-, gene-, and regionlevel mutations, uses CNN layers to extract local mutation patterns, and employs Transformer self-attention to learn long-range genomic dependencies before feature fusion and drug-speci...