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Johnny Vertiz

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Open access Sep 2026

A Meiotic B-type Cyclin Selectively Drives Mitotic Progression and Fidelity in Cancer Cells

Cell cycle transitions are driven by cyclins in complex with cyclin-dependent kinases (CDK). Here, we demonstrate that cyclin B3, an evolutionarily divergent B-type cyclin previously thought to function exclusively in female meiosis, is expressed in mitotic cells and interacts with both CDK1 and CDK2. We show that cycl...

Amrutha Kizhedathu, Anh Cao Ngoc Nguyen, Clinton Yu et al. · 0 citations

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