Open access
Sep 2026
Integrative prediction of Alzheimer's disease and related dementias using multi‐omics aging clocks and genetic data
Abstract INTRODUCTION We tested whether combining Alzheimer's disease and related dementias (ADRD) polygenic risk scores (PRS) with biological aging markers improves ADRD risk prediction. METHODS In 16,215 UK Biobank (UKB) participants free of ADRD at baseline (median follow‐up: 10.08 years), 397 incident diagnoses wer...
S. Mostafaei, Karolina Gustavsson, Hampus Hagelin et al.
· Alzheimer's & Dementia · 0 citations