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Author

Jonathan R. I. Coleman

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Open access Sep 2025

Mapping the genetic landscape of the age at onset and severity of eating disorder symptoms

Background Eating disorder treatment is most successful when delivered at first onset, underscoring the importance of early intervention. UK patients transition from child to adult services at age 18, a process often poorly supported. Genetic factors may contribute to earlier onset, but molecular genetic research into...

H. Davies, A. T. ter Kuile, Zain-Ul-Abideen Ahmad et al. · 0 citations
Open access Oct 2026

Mapping the genetic landscape of the age at onset and severity of eating disorder symptoms.

BACKGROUND Eating disorder treatment is most successful when delivered at first onset, underscoring the importance of early intervention. Genetic factors may contribute to earlier onset, but molecular genetic research into symptom onset and severity remains limited. AIMS We investigated: (a) age at onset of behaviour...

H. Davies, A. T. ter Kuile, Zain-Ul-Abideen Ahmad et al. · 0 citations
Aug 2026

Binge-eating behavior and anorexia nervosa have shared and distinct genetic components

Although both eating disorder phenotypes correlate genetically with other psychiatric conditions, binge eating also correlates with impulsivity, earlier age at first menstrual cycle and increased body mass, whereas anorexia nervosa shares genetics with metabolic traits.

Jonathan R. I. Coleman, H. Davies · 0 citations
Open access Sep 2026

Identifying differential interactions of potentially traumatic experiences with genetic risk for posttraumatic stress disorder

ABSTRACT Background: Posttraumatic stress disorder (PTSD) occurs following potentially traumatic experiences, but not everyone who experiences trauma develops PTSD. Genetic factors play an important role in shaping how individuals respond to trauma, reflecting gene-environment interaction. An open and important questio...

Jacob Knyspel, S. Kakar, Anna C. Carnegie et al. · 0 citations
Open access Aug 2026

Genomic dimensions deconstruct the clinical heterogeneity of bipolar disorder

Bipolar disorder’s genetic architecture appears hierarchical—a general liability resolving into dimensions of course and comorbidity, beyond subtypes, beyond subtypes.

Tracey van der Veen, M. Tesfaye, J. M. K. Yang et al. · 0 citations

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