Joran Deschamps

Super-resolution mapping of platelet α-granules uncovers non-polarized secretion and differential retention of VWF and thrombospondin-1

Platelet α-granules contain hundreds of bioactive proteins that regulate thrombosis, inflammation and tissue repair. The interplay between α-granule secretion and platelet biomechanics is central to platelet function but remains incompletely understood. Here we combined complementary super-resolution microscopy methods...