Open access
Sep 2026
Peripheral Blood as the Sole Source for Cancer Neoantigen and Reactive T-Cell Discovery.
Neoantigen-targeted T-cell therapies require invasive tumor biopsies to identify neoantigens and reactive T cells, limiting their applicability and potentially underestimating tumor heterogeneity. We propose a novel strategy relying solely on peripheral blood to identify non-synonymous mutations via cell-free DNA whole...
Andrea García-Garijo, I. Creus-González, Pierre L. Levy et al.
· Cancer Discovery · 0 citations