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Author

José M Villalba

1 paper indexed here

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Open access Jul 2026

SARS-CoV-2 ORF7a drives mitochondrial dysfunction via PDK4 activation and complex I inhibition.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection reprograms host metabolism to favor viral replication and immune evasion, yet the contribution of accessory proteins remains poorly defined. Here, we characterize the metabolic effects of the SARS-CoV-2 accessory protein ORF7a. Lentiviral expression...

Raúl Fernández-Rodríguez, Carmen M. Soto-Jiménez, Rebeca Acín-Pérez et al. · 0 citations

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