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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Joseph Nasser

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Open access Sep 2026

Quantitative changes in 3D contact predict changes in enhancer-promoter regulation upon cohesin depletion

Enhancers are drivers of gene regulation thought to act via 3D interactions with promoters. However, genome-wide cohesin depletion causes only limited changes in gene expression, despite widespread loss of contact domains, raising questions about how 3D contacts and cohesin influence enhancer function. Here, we intro...

Philine Guckelberger, Benjamin R. Doughty, Suhas S. P. Rao et al. · 0 citations
Open access Jul 2026

An encyclopedia of human enhancer–gene regulatory interactions

An encyclopedia of enhancer–gene regulatory interactions in the human genome is built, revealing global properties of enhancer networks, identifying differences in regulatory complexity across genes, and improving analyses linking noncoding variants to target genes and cell types for common, complex diseases.

A. Gschwind, Kristy S. Mualim, Alireza Karbalayghareh et al. · 6 citations

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