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Author

Joseph V. Bonventre

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2 papers indexed here

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Open access Oct 2026

Group IVA Cytosolic Phospholipase A2 (cPLA2α): Pharmacological Inhibition Attenuates Kidney Inflammation and Fibrosis

Chronic kidney disease (CKD) is a significant global health burden and a leading cause of death in the United States. Chronic inflammation contributes to fibrosis and CKD progression. Here, we present evidence that a key pro-inflammatory group IVA phospholipase A2 enzyme (cPLA2α) is critical to the development of kidne...

Berit Johansen, Said Movahedinaini, L. Selvik et al. · 0 citations
Review Sep 2026

Kidney Injury Molecule: a Biomarker and much more.

Kidney injury molecule 1 (KIM-1), encoded by HAVCR1, was initially identified as one of the most highly induced proteins in injured proximal tubule epithelial cells and subsequently established as a sensitive tissue, urinary, and circulating biomarker of kidney injury. Yet KIM-1 is not just a marker of epithelial damag...

Ahmed Soliman, T. Ichimura, Joseph V. Bonventre · 0 citations

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