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Josh L. Espinoza

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Open access Oct 2026

Leviathan: fast, memory-efficient, and scalable taxonomic and pathway profiling for (pan)genome-resolved metagenomics and metatranscriptomics

ABSTRACT Functional profiling of meta-omics is essential for understanding microbial communities, yet support for custom genome-resolved reference databases is limited. We introduce Leviathan for integrated taxonomic and functional profiling at both genome and pangenome resolution. Leviathan combines Sylph for ultrafas...

Josh L. Espinoza, Allan J. Phillips, C. Dupont · 0 citations

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