Author

Joshua A. Baccile

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Open access Sep 2026

Photoreactive Pantetheinyl Mimics Reveal Design Limitations for Crypto‐Acyl Carrier Proteins

Polyketide synthases (PKS), fatty acid synthases (FAS), and non‐ribosomal peptide synthetases (NRPS) span a variety of protein architectures and catalytic modalities. Common to all these biosynthetic modalities is the centrality of a phosphopantetheinylated carrier protein, which shuttles substrate either inter‐ or int...

Anna-Kay R. West, Tawakalitu A. Afolabi-Balogun, Christian C. Martin et al. · ChemBioChem · 0 citations

Open access Sep 2026

The ferredoxin/flavodoxin-NADP + oxidoreductase YumC is essential for isoprenoid and peptidoglycan biosynthesis in Bacillus subtilis

An essential role is defined for Bacillus subtilis YumC, a member of a distinct group of bacterial FNRs that resemble thioredoxin reductase, and how the varied roles of redox systems among bacteria depend upon metabolic context is illustrated.

Deniz Akbulut, Marirene Chacón-Arnaude, Dillon P. McBee et al. · bioRxiv · 0 citations