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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

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Joshua B. Sheetz

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Open access Sep 2026

Modulating pseudokinase conformation from the ATP-binding site

SUMMARY Pseudokinase domains (PsKDs) mediate key signaling processes involved in human disease. Despite transformative success in targeting catalytically active protein kinases, drug development for pseudokinases has lagged behind. Although they lack catalytic activity, pseudokinases are conformationally dynamic and ar...

Joshua B. Sheetz, Yuko Tsutsui, Kumar D. Ashtekar et al. · 0 citations

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