Author

Joshua E. Elias

2 papers indexed here

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Open access Aug 2026

An in vivo resource of age-regulated C. elegans intestinal secretory-pathway proteins highlights secreted enzymes associated with lifespan regulation.

Secreted proteins are essential to modulate homeostasis in the extracellular space and facilitate communication to distal cells or tissues. Yet, the identity and functional importance of extracellular proteins in aging have been understudied. Here we use proximity labeling followed by quantitative proteomics to systema...

J. Miklas, Katharina Papsdorf, Eric D. Sun et al. · Cell Reports · 0 citations

Open access Sep 2026

Arrayed hydrogels pair whole-cell imaging with single-cell mass spectrometry proteomics

Multimodal single-cell analysis aims to elucidate cellular-level phenotype within heterogeneous cell populations. Advancements in single-cell proteomics (SCP) seek to deepen quantitative depth, coverage, and reproducibility for a robust view of functional cell state. However, broadly accessible multimodal approaches ar...

M. Overton, C. Deroy, Eileen Wang et al. · bioRxiv · 0 citations