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Joshua Glazier

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Open access Aug 2026

Programmable genetic control of tumor-colonizing Bifidobacterium longum for intratumoral therapeutic delivery and biocontainment

Engineered bacteria offer a distinct modality for cancer therapy by exploiting the ability of certain species to colonize tumors and deliver therapeutic payloads. Improving their efficacy and safety requires control over bacterial activity after tumor colonization, yet few microbial chassis permit it. Bifidobacterium l...

Jaehyun Lee, Joshua Glazier, R. Weichselbaum et al. · 0 citations

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