Open access
Jul 2026
Single-cell multimodal profiling of pan-cancer cell lines uncovers gene regulatory principles underlying intrinsic cell states and environmental features
A pan-cancer single cell transcriptomic and epigenomic atlas is generated and subtype-specific gene-regulatory programs that shape cancer cell-state plasticity are identified that shape cancer cell-state plasticity.
Zihan Xu, Aileen Ugurbil, Joshua Kwan et al.
· Nature Communications · 0 citations