Review
Open access
Jul 2026
Pridopidine Mediated Sigma-1 Receptor Activation and Therapeutic Implications in Neurodegenerative Diseases
Neurodegenerative diseases are targets for pridopidine therapy, which aims to improve quality of life through neuroprotective mechanisms that involve sigma-1 receptor (S1R) activation. Neurodegenerative motor and cognitive diseases are influenced by dopamine imbalance, where disruptions in pathways contribute to states...
Ahmed I. Anwar, Abdul-Rahman A. Hegazi, Hamsa Priya Bhuchakra et al.
· Neurology International · 0 citations