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Author

Jovan David Rebolledo-Mendez

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#diffusion models Open access Oct 2026

Directed Laplacian from tracer polarity for connectome models of neurodegenerative spread, with a nonlocal-versus-local correction and clearance as a conditional future aim

Dated research note. The claim is that the next network-diffusion model for prion-like pathology spread on a primate connectome should be a directed graph Laplacian whose edge polarity is taken from tract-tracing data rather than from diffusion MRI, with separate anterograde and retrograde operators and their ratio lef...

Jovan David Rebolledo-Mendez · 0 citations
#diffusion models Open access Oct 2026

NeuroModular AI Architecture — 2026 Update: Connectome-Constrained Modular Language Models with Disease-Trajectory Lesion Validation

Research note updating the author's May 2025 NeuroModular AI Architecture concept (region-specific models communicating through a connectome-informed backbone). It acknowledges recent prior art on brain-inspired modular LLM systems (MAP, MICRO, Lilith and others) and claims no priority over it. It fixes four specific c...

Jovan David Rebolledo-Mendez · 0 citations
#diffusion models Open access Oct 2026

Nonlocality as the Price of Discovery: A Symmetry Between Transport Operators in Neurodegeneration and Attention in Language Models

Short framing note. It observes that two independent modeling corrections are the same statement: in neurodegeneration, a streamline-weighted graph Laplacian is a nonlocal transport operator while voxelwise anisotropic diffusion is local; in language models, all-to-all attention is a nonlocal interaction while topograp...

Jovan David Rebolledo-Mendez · 0 citations

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