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Juan Antonio Madrid

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Open access Aug 2026

Impact of Human Melanopsin Gene (OPN4) Polymorphisms (I394T, P10L) on Nocturnal Melatonin and Daily Rhythms in Young Adults

The findings suggest that I394T‐C carriers exhibit features of the circadian phenotype commonly observed in older cohorts, including reduced rhythm robustness and lower melatonin levels, and support a role for this variant in interindividual differences in light sensitivity and circadian function.

Jesús Vicente-Martínez, M. Bonmati-Carrion, Ana María López-Parra et al. · 0 citations