Background: Pulmonary fibrosis (PF) involves remodeling of lung architecture and limited therapeutic options are available. Sirtuin 1 (SIRT1), an epigenetic regulator, has emerged as a promising antifibrotic target due to its role in apoptosis, inflammation, and chromatin remodeling. Methods: We evaluated the effects o...
Liliana Faridi Saavedra-Salazar, Nayabei Ruiz Ramirez, Hugo Christian Monroy-Rami Rez et al.· American Journal of Physiolo...· 0 citations
Obesity promotes chronic inflammation and insulin resistance, disrupting key metabolic hormones (e.g., insulin and leptin) and triggering metabolic dysfunction-associated steatohepatitis (MASH). Obesity is commonly associated with cardiovascular disease. Autophagy preserves heart function in response to various stresse...
D. López-Cifuentes, A. Sandoval-Rodríguez, Rebeca Escutia-Gutiérrez et al.· Journal of Translational Med...· 0 citations
Evaluated the distribution of atypical memory B cells in patients with SjD and showed that aMBCs displayed heightened CD38 expression, signaling an activated phenotype primed for plasma cell differentiation, underscores the aNAV-DN2 axis as a central hallmark of B-cell dysregulation in SjD.
Victor Manuel Menchaca-Tapia, P. Ortiz-Lazareno, N. Espinoza-García et al.· Scientific Reports· 0 citations
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