Female-Biased IL-17–STAT3 Signaling Marks Dementia-Associated Microglial Inflammation in Alzheimer’s Disease
INTRODUCTION Alzheimer’s disease (AD) disproportionately affects women, but the underlying mechanisms are not fully understood. We compare sex-specific molecular changes across AD with and without dementia at single-cell resolution. METHODS We performed sex-stratified single-nucleus transcriptomic analysis of human AD...