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Nov 2026

Characterization of Pulmonary Tropism, Expression Kinetics and Safety of the Novel Adeno-Associated Virus-LungM3 Vector.

This study investigated the lung-targeting characteristics, dose- and time-dependent effects, and safety of a novel engineered adeno-associated virus (AAV) vector, AAV-LungM3. In vitro, mouse primary lung organoids were transduced with AAV-LungM3 at doses of 103, 104, and 105 vector genomes (vg)/cell, and transduction...

Heng-Hai Nie, Juan Du, Xi-Feng Feng et al. · 0 citations

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