Review
Open access
Jul 2026
The NLRP3 inflammasome as a dynamic context-dependent regulator: mechanisms, disease progression, and therapeutic implications.
This review examines NLRP3 biology across three interconnected dimensions: cellular context, including immune and non-immune compartments; microenvironmental context, including infectious versus sterile inflammation and tissue repair versus tissue damage; and disease context, including stage- and time-dependent functio...
Shuo Liu, Xun Liu, Jing Hu et al.
· Journal of Translational Med... · 0 citations